白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)
Multiplex Assay Kit for Interleukin 10 (IL10) ,etc. by FLIA (Flow Luminescence Immunoassay)
CSIF; IL10A; TGIF; Cytokine Synthesis Inhibitory Factor
（注：?jiǎn)未位鞙y(cè)多因子不超過(guò)8個(gè)指標(biāo) ）
- 編號(hào)LMA056Ca
- 物種Canis familiaris; Canine (Dog，犬)相同的名稱(chēng)，不同的物種。
- 實(shí)驗(yàn)方法雙抗夾心
- 反應(yīng)時(shí)長(zhǎng)3.5h
- 檢測(cè)范圍0.98-1000pg/mL
- 靈敏度最小可檢測(cè)劑量小于等于0.327 pg/mL.
- 樣本類(lèi)型Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids
- 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格8指標(biāo)數(shù)7指標(biāo)數(shù)6指標(biāo)數(shù)5指標(biāo)數(shù)4指標(biāo)數(shù)3指標(biāo)數(shù)2指標(biāo)數(shù)1指標(biāo)數(shù)
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
本試劑盒用于檢測(cè)白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)，經(jīng)檢測(cè)與其它相似物質(zhì)無(wú)明顯交叉反應(yīng)。
由于受到技術(shù)及樣本來(lái)源的限制，不可能完成對(duì)所有相關(guān)或相似物質(zhì)交叉反應(yīng)檢測(cè)，因此本試劑盒有可能與未經(jīng)檢測(cè)的其它物質(zhì)有交叉反應(yīng)。
回收率
分別于定值血清及血漿樣本中加入一定量的白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)（加標(biāo)樣品），重復(fù)測(cè)定并計(jì)算其均值，回收率為測(cè)定值與理論值的比率。
| 樣本 | 回收率范圍(%) | 平均回收率(%) |
| serum(n=5) | 96-103 | 101 |
| EDTA plasma(n=5) | 91-103 | 98 |
| heparin plasma(n=5) | 85-101 | 97 |
精密度
精密度用樣品測(cè)定值的變異系數(shù)CV表示。CV(%) = SD/mean×100
批內(nèi)差：取同批次試劑盒對(duì)低、中、高值定值樣本進(jìn)行定量檢測(cè),每份樣本連續(xù)測(cè)定20 次，分別計(jì)算不同濃度樣本的平均值及SD值。
批間差：選取3個(gè)不同批次的試劑盒分別對(duì)低、中、高值定值樣本進(jìn)行定量測(cè)定，每個(gè)樣本使用同一試劑盒重復(fù)測(cè)定8次，分別計(jì)算不同濃度樣本的平均值及SD值。
批內(nèi)差： CV<10%
批間差： CV<12%
線性
在定值血清及血漿樣本內(nèi)加入適量的白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)，并倍比稀釋成1:2，1:4，1:8，1:16的待測(cè)樣本，線性范圍即為稀釋后樣本中白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)含量的測(cè)定值與理論值的比率。
| 樣本 | 1:2 | 1:4 | 1:8 | 1:16 |
| serum(n=5) | 89-103% | 84-94% | 78-91% | 87-98% |
| EDTA plasma(n=5) | 87-94% | 79-95% | 81-93% | 79-91% |
| heparin plasma(n=5) | 92-99% | 87-96% | 81-99% | 86-95% |
穩(wěn)定性
經(jīng)測(cè)定，試劑盒在有效期內(nèi)按推薦溫度保存，其活性降低率小于5%。
為減小外部因素對(duì)試劑盒破壞前后檢測(cè)值的影響，實(shí)驗(yàn)室的環(huán)境條件需盡量保持一致，尤其是實(shí)驗(yàn)室內(nèi)溫度、濕度及溫育條件。其次由同一實(shí)驗(yàn)員來(lái)進(jìn)行操作可減少人為誤差。
實(shí)驗(yàn)流程
1. 實(shí)驗(yàn)前標(biāo)準(zhǔn)品、試劑及樣本準(zhǔn)備；
2. 加樣（標(biāo)準(zhǔn)品、樣本、磁珠）標(biāo)準(zhǔn)品或樣本100μL及磁珠10μL，
37°C酶標(biāo)板振蕩器孵育90分鐘；
3. 磁吸甩干，加檢測(cè)溶液A100μL，37°C酶標(biāo)板振蕩器孵育60分鐘；
4. 磁吸洗板3次；
5. 加檢測(cè)溶液B100μL，37°C振動(dòng)孵育30分鐘；
6. 磁吸洗板3次；
7. 加鞘液100μL，旋渦震蕩2分鐘后讀數(shù)。
實(shí)驗(yàn)原理
將白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)抗體包被于磁珠，制成固相載體，向微孔中分別加入標(biāo)準(zhǔn)品或標(biāo)本以及磁珠，其中的白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)與連接于固相載體上的抗體結(jié)合，然后加入生物素化的白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)抗體，將未結(jié)合的生物素化抗體洗凈后，加入PE標(biāo)記的親和素，再次徹底洗滌后即可上機(jī)讀數(shù)。MFI值和樣品中的白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)呈正相關(guān)。
贈(zèng)品
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Canis familiaris; Canine (Dog，犬) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA056Ca01 | 白介素10(IL10)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APA056Ca61 | 白介素10(IL10)活性蛋白 | Cell?culture;?Activity?Assays. |
| EPA056Ca61 | 白介素10(IL10)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA056Ca01 | 白介素10(IL10)多克隆抗體 | WB |
| PAA056Ca06 | 白介素10(IL10)多克隆抗體 | WB; IHC; ICC; IP. |
| MAA056Ca21 | 白介素10(IL10)單克隆抗體 | WB |
| MAA056Ca22 | 白介素10(IL10)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA056Ca26 | 白介素10(IL10)單克隆抗體 | WB |
| MEA056Ca | 白介素10(IL10)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEA056Ca | 白介素10(IL10)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA056Ca | 白介素10(IL10)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| KSA056Ca01 | 白介素10(IL10)檢測(cè)試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法) | 自己動(dòng)手制作ELISA試劑盒的主要材料 |
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| Archives of Virology | Genetic and immunogenicity analysis of porcine circovirus type 2 strains isolated in central China[Pubmed:29305646] |
| Theriogenology | Effect of tropical thermal stress on peri-implantation immune responses in cows[Pubmed:29625402] |
| Evidence-based?Complementary and Alternative?Medicine | Bushenkangshuai Tablet Reduces Atherosclerotic Lesion by Improving Blood Lipids Metabolism and Inhibiting Inflammatory Response via TLR4 and NF-κB Signaling?…[Pubmed:29619063] |
| Evidence-Based?Complementary and Alternative Medicine | Tualang Honey Reduced Neuroinflammation and Caspase-3 Activity in Rat Brain after Kainic Acid-Induced Status Epilepticus[Pubmed:30108663] |
| Journal of?Animal?Physiology and?Animal?Nutrition | The effect of feed supplementation with a copper‐glycine chelate and copper sulphate on selected humoral and cell‐mediated immune parameters, plasma?…[Pubmed:28603872] |
| Experimental and Therapeutic Medicine | S?adenosyl methionine regulates calcium channels and inhibits uterine smooth muscle contraction in rats with infectious premature delivery through the transient?…[Pubmed:29896230] |
| Pakistan Veterinary Journal | Comparison of Plasma Interleukin-6 and Interleukin-10 Concentrations between Female Dogs with Mammary Gland Tumours and Healthy[17-377.pdf] |
| Journal of?International?Medical?Research | Changes in Th1/Th2-producing cytokines during acute exacerbation chronic obstructive pulmonary disease[Pubmed:29950127] |
| Tropical?Animal?Health?andProduction | Effect of reproductive disorders on productivity and reproductive efficiency of dromedary she-camels in relation to cytokine concentration[Pubmed:29423707] |
| Biotechnic & Histochemistry | Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats[Pubmed: 30234391] |
| Cytokine | Natural killer T cell ligand alpha-galactosylceramide protects against gut ischemia reperfusion-induced organ injury in mice[Pubmed: 30195979] |
| Life?Sciences | Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats[Pubmed: 30205096] |
| International?Journal?of?Clinical?and?Experimental?Medicine | The relationship between autophagy and apoptosis of lamina propria dendritic cells from the small intestine on the immunodynamics of sepsis mice[] |
| European?Journal of Pharmacology | Inhibition of Rho kinase by GSK 269962 reverses both corticosterone-induced detrusor overactivity and depression-like behaviour in rats[Pubmed: 30172788] |
| Veterinary Microbiology | PD-1 blockade inhibits lymphocyte apoptosis and restores proliferation and anti-viral immune functions of lymphocyte after CP and NCP BVDV infection in vitro[Doi: 10.1016/j.vetmic.2018.10.014] |
| Immunology | DNA prime‐protein boost vaccine encoding HLA‐A2,‐A24 and‐DR 1 restricted epitopes of Ca NA 2 against visceral leishmaniasis[] |
| Veterinary?Immunology?and?Immunopathology | Evaluation of T regulatory lymphocytes and serum concentration of selected cytokines in dogs with perianal tumors[] |
| Research?in Veterinary?Science | Levels of selected cytokines and acute–phase proteins in the serum of dairy cows with cystic ovarian disease and those in follicular and luteal phases of normal?…[Pubmed: 30580231] |
| Biology?of?Reproduction | Recombinant adiponectin alleviates abortion in mice by regulating Th17/Treg imbalance via p38MAPK-STAT5 pathway[Pubmed: 30496353] |
| BBA- Molecular Basis of Disease | Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic?…[Pubmed: 30553018] |
| Archives of Physiology and Biochemistry | Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin[Pubmed: 30513216] |
| Journal of Veterinary?Research | Early cytokine response after vaccination with Coxiella burnetii phase I in an infected herd of dairy cattle[] |
| Journal?of?Hepatology | Chronic hyperammonemia induces peripheral inflammation that leads to cognitive impairment in rats: reversal by anti-tnfa treatment[Pubmed: 30654069] |
| Food?&?Function | Ovotransferrin ameliorates the dysbiosis of immunomodulatory function and intestinal microbiota induced by cyclophosphamide[Pubmed: 30724290] |
| Journal of?Neuroinflammation | Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer's disease[Pubmed: 30777084] |
| Biomedicine & Pharmacotherapy | Three types of gut bacteria collaborating to improve Kui Jie'an enema treat DSS-induced colitis in mice[Pubmed: 30870717] |
| Experimental?Biology?and?Medicine | Grape seed proanthocyanidin extract alleviates arsenic-induced lung damage through NF-κB signaling[Pubmed: 30869553] |
| 拉脫維亞科學(xué)院院刊 | Influence of Antibiotic-Impregnated Biomaterials on Inflammatory Cytokines[] |
| BioMed Research International | Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway[] |
| Scientific Reports | Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice[Pubmed: 30962497] |
| Journal of?Pineal?Research | Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in mice[Pubmed: 30929267] |
| Life?Sciences | 1, 25-(OH) 2D3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-κB pathway[Pubmed: 30928409] |
| ACS?Biomaterials-Science?&?Engineering | Photothermal-triggered Controlled Drug Release From Mesoporous Silica nanoparticles Based On Base-pairing Rules[] |
| Life?Sciences | ERK activation by zeranol has neuroprotective effect in cerebral ischemia reperfusion[Pubmed: 31005550] |
| ARCHIVES OF?ORAL?BIOLOGY | Histopathological and Biochemical Evaluation of the effect of Paeoniflorin on the Periodontium During and After Periodontitis Formation in Rats[Pubmed: 31005686] |
| Behavioural Brain Research | THE ROLE OF ANTI-INFLAMMATORY CYTOKINES IN MEMORY PROCESSING IN A HEALTHY BRAIN[] |
| Toxicon | The wound healing potential of a pro-angiogenic peptide purified from Indian Russell's viper (Daboia russelii) venom[Pubmed: 31054289] |
| 中國(guó)免疫學(xué)雜志 | TRAF-6 調(diào)控TGF-β1-Smad2/Smad3 信號(hào)通路在Graves 病免疫發(fā)病機(jī)制中的作用[] |
| Investigación Clínica | The impact of IL-10 gene polymorphism 1082A/G (rs1800896) on increased IL-10 secretion in patients with chronic kidney disease in the Kurdistan Region of?…[] |
| Food & Function | Network pharmacology oriented study reveals inflammatory state-dependent dietary supplement hepatotoxicity responses in normal and diseased rats[Pubmed: 31140472] |
| INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | Antibacterial immunomodulatory and antibiofilm triple effect of Salivaricin LHM against Pseudomonas aeruginosa urinary tract infection model[Pubmed: 31136751] |
| Journal of the Royal Army Medical Corps | CD28 deficiency attenuates primary blast-induced renal injury in mice via the PI3K/Akt signalling pathway[Pubmed: 31129646] |
| Pinealektomize Edilmi? Septik S??anlarda TNF-α, IL-6, IL-10 ve IL-1β'nin Kan Düzeyleri ile Karaci?er ve B?brekte Gen Ekspresyonu Seviyelerindeki?…[Doi: 10.5505/vtd.2019.32815] | |
| international immunopharmacology | Adenovirus-mediated down-regulation of miR-21-5p alleviates experimental autoimmune uveoretinitis in mice[Pubmed: 31228813] |
| Chemosphere | Atmospheric H2S triggers immune damage by activating the TLR-7/MyD88/NF-κB pathway and NLRP3 inflammasome in broiler thymus[] |
| Biomedicine & Pharmacotherapy | MODULATION OF LIPOPOLYSACCHARIDE-INDUCED CYTOKINES RESPONSE IN MICE BY GRAVIOLA LEAF POWDER[] |
| Free Radical Biology and Medicine | Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat[Pubmed: 31255668] |
| international journal of molecular medicine | Alcohol?induced attenuation of post?traumatic inflammation is not necessarily liver?protective following trauma/hemorrhage[Pubmed: 31257463] |
| Environmental Toxicology and Pharmacology | Protective effect of Vitamin D3 against lead induced hepatotoxicity, oxidative stress, immunosuppressive and calcium homeostasis disorders in rat[] |
| Life Sciences | Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis[Pubmed: 31465731] |
| Animals | Anti-Inflammatory State in Arabian Horses Introduced to the Endurance Training[Pubmed: 31462005] |
| Developmental & Comparative Immunology | CD38 play roles in T cell-dependent response and B cell differentiation in nile tilapia (Oreochromis niloticus)[Pubmed: 31605715] |
| Scientific Reports | Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus[Pubmed: 31578381] |
| Journal of Medicinal Food | Polysaccharide from the Seeds of Plantago asiatica L. Protect Against Lipopolysaccharide-Induced Liver Injury[Pubmed: 31560611] |
| International Journal of Molecular Medicine | Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway[Pubmed: 31545485] |
| BMC Complementary and Alternative Medicine | Qingkailing injection ameliorates cerebral ischemia-reperfusion injury and modulates the AMPK/NLRP3 Inflammasome Signalling pathway[Pubmed: 31747940] |
| parasitology research | Enhancement of the therapeutic efficacy of praziquantel in murine Schistosomiasis mansoni using silica nanocarrier[Pubmed: 31673833] |
| International Immunopharmacology | Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injury[Pubmed: 31835081] |
| Journal of Tissue Engineering and Regenerative Medicine | Intra‐tendon delivery of leukocyte‐rich platelet‐rich plasma at early stage promotes tendon repair in a rabbit Achilles tendinopathy model[Pubmed: 31840415] |
| Pigment Cell & Melanoma Research | Altered expression of nuclear factor of activated T cells, Forkhead Box P3 and immune suppressive genes in regulatory T cells of generalized vitiligo patients[Pubmed: 31917889] |
| Cytokine | Levels of pro-and anti-inflammatory cytokines in cystic fibrosis patients with or without gingivitis[Pubmed: 31927460] |
| Frontiers in Immunology | The Increase in IL-1β in the Early Stage of Heatstroke Might Be Caused by Splenic Lymphocyte Pyroptosis Induced by mtROS-Mediated Activation of the?…[Pubmed: 31921131] |
| Transboundary and Emerging Diseases | Pathogenicity of porcine reproductive and respiratory syndrome virus (ORF5 RFLP 1–7–4 viruses) in China[Pubmed: 32187856] |
| Nanomedicine | The toxicity of alumina nanoparticles to immune system in mice[Pubmed: 32162999] |
| Scientific Reports | Serum sHLA-G: Significant diagnostic biomarker with respect to therapy and immunosuppressive mediators in Head and Neck Squamous Cell Carcinoma[Pubmed: 32123232] |
| Biomed Pharmacother | Suppression of Fpr2 expression protects against endotoxin-induced acute lung injury by interacting with Nrf2-regulated TAK1 activation[Pubmed: 32106380] |
| Antibiotics | Effects of Early Intervention with Antibiotics and Maternal Fecal Microbiota on Transcriptomic Profiling Ileal Mucusa in Neonatal Pigs[Pubmed: 31963653] |
| JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | Nonsteroidal anti‐inflammatory drugs alleviate severity of post‐ERCP pancreatitis by inhibiting inflammation and reducing apoptosis[Pubmed: 32064683] |
| Prog Neuropsychopharmacol Biol Psychiatry | Progress in Neuropsychopharmacology & Biological Psychiatry[Pubmed: 17134810] |
| Biomed Research International | Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB …[Pubmed: 32071922] |
| Molecular and Cellular Biochemistry | Calycosin-7-O-β-d-glucoside attenuates myocardial ischemia–reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in …[Pubmed: 31712941] |
| Silkworm pupa oil attenuates acetaminophen‐induced acute liver injury by inhibiting oxidative stress‐mediated NF‐κB signaling[Pubmed: 31993149] | |
| Irisin Improves Autophagy of Aged Hepatocytes via Increasing Telomerase Activity in Liver Injury[Pubmed: 31976032] | |
| molecular immunology | STAT5a induces endotoxin tolerance by alleviating pyroptosis in kupffer cells[Pubmed: 32298872] |
| Stem Cells International | Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2?…[Pubmed: 32300366] |
| Biomarkers | Management of Citrus sinensis peels for protection and treatment against gastric ulcer induced by ethanol in rats[Pubmed: 32319821] |
| CLINICAL AND EXPERIMENTAL OTORHINOLARYNGOLOGY | Effects of Amniotic Membrane Extract on the Hyperplastic Response of the Middle Ear Mucosa in a Bacterially-Induced Otitis Media Rat Model: A Preliminary Study[Pubmed: 32279472] |
| oral diseases | Clinical Importance of Neuregulin‐4 and Its Receptor ErbB4 in Periodontal Disease Pathogenesis[Pubmed: 32274847] |
| INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | Gastroprotective effect of Lycium barbarum polysaccharides and C-phyocyanin in rats with ethanol-induced gastric ulcer[Pubmed: 33058973] |
| JOURNAL OF GENE MEDICINE | Rabbit umbilical cord mesenchymal stem cells: A New Option for tissue engineering[Pubmed: 33047422] |
| BIOMEDICINE & PHARMACOTHERAPY | Chlorogenic acid prevents acute myocardial infarction in rats by reducing inflammatory damage and oxidative stress[Pubmed: 33022535] |
| Heliyon | Effect of procyanidins on lipid metabolism and inflammation in rats exposed to alcohol and iron[Pubmed: 32964156] |
| Int J Neurosci | Downregulation of ROCK2 attenuates alcohol-induced inflammation and oxidative stress in astrocytes[Pubmed: 32942936] |
| THERIOGENOLOGY | Porcine soluble CD83 alleviates LPS-induced abortion in mice by promoting Th2 cytokine production, Treg cell generation and trophoblast invasion[Pubmed: 32810792] |
| Theriogenology | A comparative study on various immunological parameters influencing embryo survivability in crossbred dairy cows[Pubmed: 32810791] |
| JOURNAL OF MOLECULAR NEUROSCIENCE | Different Activation of IL-10 in the Hippocampus and Prefrontal Cortex During Neurodegeneration Caused by Trimethyltin Chloride[Pubmed: 32803646] |
| BRAIN BEHAVIOR AND IMMUNITY | Active smoking, sleep quality and cerebrospinal fluid biomarkers of neuroinflammation[Pubmed: 32717405] |
| Bioengineered | Down-regulation of ROCK2 alleviates ethanol-induced cerebral nerve injury partly by the suppression of the NF-κB signaling pathway[Pubmed: 32684089] |
| EXPERIMENTAL DERMATOLOGY | Decreased suppression of CD8+ and CD4+ T cells by peripheral Regulatory T cells in Generalized Vitiligo due to reduced NFATC1 and FOXP3 proteins[Pubmed: 32682346] |
| Parasites & Vectors | Fasciola gigantica excretory-secretory products (FgESPs) modulate the differentiation and immune functions of buffalo dendritic cells through a mechanism?…[Pubmed: 32680553] |
| Life Sci | Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo study[Pubmed: 32652140] |
| Front Pharmacol | Cyclic Peptide Extracts Derived From Pseudostellaria heterophylla Ameliorates COPD via Regulation of the TLR4/MyD88 Pathway Proteins[Pubmed: 32581806] |
| BIOTECHNOLOGY LETTERS | Recombinant ferritin nanoparticles can induce dendritic cell maturation through TLR4/NF-κB pathway[Pubmed: 32567013] |
| INTERNATIONAL IMMUNOPHARMACOLOGY | A potential drug combination of omeprazole and patchouli alcohol significantly normalizes oxidative stress and inflammatory responses against gastric ulcer in ethanol …[Pubmed: 32559721] |
| Int J Mol Sci | Effects of PDE3 Inhibitor Olprinone on the Respiratory Parameters, Inflammation, and Apoptosis in an Experimental Model of Acute Respiratory Distress Syndrome[Pubmed: 32403267] |
| BRAIN BEHAVIOR AND IMMUNITY | USP8 protects against lipopolysaccharide-induced cognitive and motor deficits by modulating microglia phenotypes through TLR4/MyD88/NF-κB signaling pathway in …[Pubmed: 32335193] |
| JAMA Surgery | Intraoperative dexmedetomidine for prevention of postoperative delirium in elderly patients with mild cognitive impairment[Pubmed: 28593326] |
| BIOMEDICINE & PHARMACOTHERAPY | Protective effects of bee bread on testicular oxidative stress, NF-κB-mediated inflammation, apoptosis and lactate transport decline in obese male rats[Pubmed: 33152939] |
| Frontiers in Pharmacology | M10, a Myricetin-3-ObD-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice[Pubmed: 33041798] |
| κ?opioid receptor agonists may alleviate intestinal damage in cardiopulmonary bypass rats by inhibiting the NF?κB/HIF?1α pathway[Pubmed: 32509012] | |
| Molecular Medicine Reports | Placenta?derived mesenchymal stem cells ameliorate lipopolysaccharide?induced inflammation in RAW264. 7 cells and acute lung injury in rats[Pubmed: 32626979] |
| Food & Function | Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial?…[] |
| Nanoscale Research Letters | Protective Effects of Carbon Dots Derived from Phellodendri Chinensis Cortex Carbonisata against Deinagkistrodon acutus Venom-Induced Acute Kidney?…[] |
| Journal of Biochemical and Molecular Toxicology | Vitamin D3 and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti‐inflammatory actions by remodeling cellular?…[] |
| Journal of Functional Foods | Wine pomace product modulates oxidative stress and microbiota in obesity high-fat diet-fed rats[] |
| Evaluation of lipopolysaccharide-induced acute lung injury attenuation in mice by Glycyrrhiza glabra[] | |
| Applied materials today | Tanshinone IIA-loaded aligned microfibers facilitate stem cell recruitment and capillary formation by inducing M2 macrophage polarization[] |
| letter in applied nanobioscience | Phytochemical and Toxicological Effect of Ethanol Extract of Heliotropium Indicum on Liver of Male Albino Rats[] |
| biosciences biotechnology research asia | Dietary Malted Barley Grain Improved Structure and Function of Spinal Cord of Mother Rats fed on a high cholesterol diet.[] |
| Phytomedicine | Menthacarin attenuates experimental colitis[] |
| ACS Biomaterials Science & Engineering | Tissue-Engineered Decellularized Allografts for Anterior Cruciate Ligament Reconstruction[] |
| Immunomodulatory effects of sCD83 via induction of TGF-β1 and IDO: an in vitro and rat orthotopic liver transplantation study[] | |
| Effects of minocycline on neuroinflammation, gut microbiome and hippocampal neurogenesis in rats with Gulf War Illness[] | |
| Minocycline Alleviate A Rat Model Of Gulf War Illness Via Altering Gut Microbiome, Attenuating Neuroinflammation And Enhancing Hippocampal Neurogenesis[] | |
| Experimental autoimmune encephalomyelitis inhibited by Huangqi Guizhi Wuwu Decoction by enhancing Th2 cytokine[] | |
| EC NEUROLOGY | Malted Barley Ameliorated Spinal Cord Injuries of Offspring of Hypercholesterolemic Mother Rats[] |
| Journal of Burn Care & Research | Umbilical cord mesenchymal stem cells (hUCMSCs) for inflammatory regulation after excision and grafting of severe burn wounds in rats[33313794] |
| Stem Cell Reviews and Reports | Prospects on the Potential In Vitro Regenerative Features of Mechanically Treated-Adipose Tissue for Osteoarthritis Care[33469783] |
| Antioxidants (Basel) | Anti-Atherogenic Effects of Orlistat on Obesity-Induced Vascular Oxidative Stress Rat Model[33562069] |
| european journal of clinical nutrition? | Effect of Lactobacillus casei on lipid metabolism and intestinal microflora in patients with alcoholic liver injury[33514869] |
| Drug Des Devel Ther | Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPAR|?-Integrin |áv|?5 Signaling Pathway[33654384] |
| Biomed Res In | Antiangiogenic Effect of Platelet P2Y12 Inhibitor in Ischemia-Induced Angiogenesis in Mice Hindlimb[33898623] |
| BIOMATERIALS | Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration[33813259] |
| BEHAVIOURAL BRAIN RESEARCH | Minocycline alleviates Gulf War Illness rats via altering gut microbiome, attenuating neuroinflammation and enhancing hippocampal neurogenesis[34000339] |
| Life Sci | Asiatic acid attenuates diabetic retinopathy through TLR4/MyD88/NF-|êB p65 mediated modulation of microglia polarization[33965378] |
| PLoS One | Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment?aIn vivo studies[33999928] |
| Drug Design Development and Therapy | Effects of Systemic Lidocaine on Postoperative Recovery Quality and Immune Function in Patients Undergoing Laparoscopic Radical Gastrectomy[33976537] |
| Life Sciences | p-Coumaric acid ameliorates ionizing radiation-induced intestinal injury through modulation of oxidative stress and pyroptosis[33915129] |
| Brain Res Bull | Melatonin ameliorates anxiety-like behaviors induced by sleep deprivation in mice: role of oxidative stress, neuroinflammation, autophagy and apoptosis[34144202] |
| IUBMB Life | HOXA5 induces M2 macrophage polarization to attenuate carotid atherosclerosis by activating MED1[34117711] |
| Anal Cell Pathol | Interleukin 10 Plays an Important Role in Neonatal Rats with Hypoxic-Ischemia Associated with B-Cell Lymphoma 2 and Endoplasmic Reticulum Protein 29[34123712] |
| Pediatr Res | Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia¨Cischemia[34050269] |
| Stem Cells International | The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin??-[33381190] |
| BioMed Research International | Ultrashort Wave Combined with Human Umbilical Cord Mesenchymal Stem Cell (HUC-MSC) Transplantation Inhibits NLRP3 Inflammasome and Improves??-[33376718] |
| cells | The Effect of the Clenbuterol?a|?2-Adrenergic Receptor Agonist on the Peripheral Blood Mononuclear Cells Proliferation, Phenotype, Functions, and Reactive Oxygen??-[33920705] |
| Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/ROR|á/NF-|êB signaling pathways[34162146] | |
| heliyon | Dobera glabra (Forssk.) Poir.(Salvadoraceae); phenolic constituents of the aqueous leaves extract and evaluation of its anti-inflammatory, analgesic activities[] |
| Open Access Macedonian Journal of Medical Sciences | The Potential of Nano Curcumin in Preventing the Formation of Artificial Antisperm Antibody in Wistar Rats through Inflammatory Pathway Regulation[] |
| Annals of the Romanian Society for Cell Biology | Comparative Study on the Pro-Inflammatory Activity of Turmeric (Curcuma longa) and flaxseed (Linumusitatissimum)[] |
| World J Tradit Chin Med | Experimental autoimmune encephalomyelitis inhibited by Huangqi Guizhi Wuwu Decoction via Th2 cytokine enhancement[] |
| Veterinary World | Comparative evaluation of cytokine and acute-phase protein concentrations in sera of dairy cows with subclinical and clinical ketosis as a different view of the ?-[] |
| biomolecules | Treadmill Running Changes Endothelial Lipase Expression: Insights from Gene and Protein Analysis in Various Striated Muscle Tissues and Serum[] |
| Int J Biol Macromol | Establishing novel roles of bifidocin LHA, antibacterial, antibiofilm and immunomodulator against Pseudomonas aeruginosa corneal infection model[34171261] |
| J Immunol Res | Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus[34395633] |
| PLoS One | Inhibition of acetic acid-induced colitis in rats by new Pediococcus acidilactici strains, vitamin producers recovered from human gut microbiota[34310635] |
| JOURNAL OF ETHNOPHARMACOLOGY | Ethanolic extract of Pyrus pashia buch ham ex. D. Don (kainth): A bioaccessible source of polyphenols with anti-inflammatory activity in vitro and in vivo[34517063] |
| Biomed Pharmacother | Allicin ameliorates renal ischemia/reperfusion injury via inhibition of oxidative stress and inflammation in rats[34426252] |
| CNS Neurosci Ther | Alterations in the gut microbiome with hemorrhagic transformation in experimental stroke[34591349] |
| J Biochem Mol Toxicol | Thymol ameliorates 5‐fluorouracil‐induced intestinal mucositis: Evidence of down‐regulatory effect on TGF‐β/MAPK pathways through NF‐κB[34665902] |
| Tissue Cell | GPNMB plays an active role in the M1/M2 balance[34800878] |
| J Periodontol | Cytokine profile in serum and gingival crevicular fluid of children with inflammatory bowel disease: A case‐control study[34730850] |
| Biofactors | Vitamin D3 enhances the effects of omega‐3 oils against metabolic dysfunction‐associated fatty liver disease in rat[34767670] |
| Inflamm Res | Dexmedetomidine exerts cerebral protective effects against cerebral ischemic injury by promoting the polarization of M2 microglia via the Nrf2/HO-1/NLRP3 pathway[34767031] |
| Brain Sci | Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial?…[34942919] |
| Journal of Immunology | Administration of a Probiotic Mixture Ameliorates Cisplatin-Induced Mucositis and Pica by Regulating 5-HT in Rats[34568500] |
| Eur J Pharm Sci | Preclinical study of methotrexate-based hydrogels versus surfactant based liquid crystal systems on psoriasis treatment[34314841] |
| The Journal of Maternal-Fetal & Neonatal Medicine | Expression of Antimicrobial Peptides and Cytokines in Human Omentum Following Abdominal Surgery[34589365] |
| Biomedicines | Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes[34829910] |
| Anesthesiology | Adverse Mechanical Ventilation and Pneumococcal Pneumonia Induce Immune and Mitochondrial Dysfunctions Mitigated by Mesenchymal Stem Cells in Rabbits[Pubmed:34965287] |
| J Inflamm Res | Clenbuterol, a Selective β2-Adrenergic Receptor Agonist, Inhibits or Limits Post-Stroke Pneumonia, but Increases Infarct Volume in MCAO Mice[Pubmed:35058704] |
| Mol Neurobiol | Translocator Protein Ligand PIGA1138 Reduces Disease Symptoms and Severity in Experimental Autoimmune Encephalomyelitis Model of Primary Progressive?…[Pubmed:35018577] |
| Int J Nanomedicine | Protective Effects of Carbon Dots Derived from Armeniacae Semen Amarum Carbonisata Against Acute Lung Injury Induced by Lipopolysaccharides in Rats[Pubmed:35023915] |
| Bioengineered | Inflammation promotes erythropoietin induced vascular calcification by activating p38 pathway[Pubmed:35168476] |
| Toxicology | Protection from Benzene-induced Immune Dysfunction in Mice[Pubmed:35090963] |
| FASEB J | proBDNF/p75NTR promotes rheumatoid arthritis and inflammatory response by activating proinflammatory cytokines[Pubmed:35129860] |
| Exp Biol Med (Maywood) | Protective antioxidative and anti-inflammatory actions of β-caryophyllene against sulfasalazine-induced nephrotoxicity in rat[Pubmed:35068213] |
| Biomed Pharmacother | Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis[Pubmed:35453007] |
| Drug Des Devel Ther | Lung-Protective Effects of Lidocaine Infusion on Patients with Intermediate/High Risk of Postoperative Pulmonary Complications: A Double-Blind Randomized?…[Pubmed:35422611] |
| Inflammopharmacology | Silymarin constrains diacetyl-prompted oxidative stress and neuroinflammation in rats: involvements of Dyn/GDNF and MAPK signaling pathway[Pubmed:35366745] |
| Veterinary Microbiology | Self-assembled BPIV3 nanoparticles can induce comprehensive immune responses and protection against BPIV3 challenge by inducing dendritic cell maturation in?…[Pubmed:35395543] |
| Journal of Nanobiotechnology | Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM[Pubmed:35351131] |
| J Clin Med | Endometrial Dysbiosis Is Related to Inflammatory Factors in Women with Repeated Implantation Failure: A Pilot Study[Pubmed:35566605] |
| J Nanobiotechnology | Cyclosporine A loaded brain targeting nanoparticle to treat cerebral ischemia/reperfusion injury in mice[Pubmed:35658867] |
| Journal of Biomaterials Applications | Photobiomodulation associated with lipid nanoparticles and hyaluronic acid accelerate the healing of excisional wounds[Pubmed:35705485] |
| Biomedicines | Deletion of Toxoplasma Rhoptry Protein 38 (PruΔrop38) as a Vaccine Candidate for Toxoplasmosis in a Murine Model[Pubmed:35740356] |
| Viruses | Synergistic Pathogenicity by Coinfection and Sequential Infection with NADC30-like PRRSV and PCV2 in Post-Weaned Pigs[Pubmed:35215787] |
| Neuromodulation: Technology at the Neural Interface | Transcutaneous Electrical Acustimulation Improved the Quality of Life in Patients With Diarrhea-Irritable Bowel Syndrome[Pubmed:35088760] |
| Antioxidants | Blue Light Alters the Composition of the Jejunal Microbiota and Promotes the Development of the Small Intestine by Reducing Oxidative Stress[Pubmed:35204158] |
| Antioxidants | Bio-Evaluation of the Wound Healing Activity of Artemisia judaica L. as Part of the Plant's Use in Traditional Medicine; Phytochemical, Antioxidant, Anti-Inflammatory?…[Pubmed:35204215] |
| Antioxidants | Therapeutic Effects of Bee Bread on Obesity-Induced Testicular-Derived Oxidative Stress, Inflammation, and Apoptosis in High-Fat Diet Obese Rat Model?…[Pubmed:35204140] |
| Oxidative Medicine and Cellular Longevity | The Role of Aeromonas-Goblet Cell Interactions in Melatonin-Mediated Improvements in Sleep Deprivation-Induced Colitis[Pubmed:35355860] |
| Frontiers in Molecular Neuroscience | Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines[Pubmed:35465093] |
| Vaccines | Age-Dependent Dynamics of Maternally Derived Antibodies (MDAs) and Understanding MDA-Mediated Immune Tolerance in Foot-and-Mouth Disease-Vaccinated?…[Pubmed:35632433] |
| Journal of Integrative Medicine | Salvadora persica extract attenuates cyclophosphamide-induced hepatorenal damage by modulating oxidative stress, inflammation and apoptosis in rats[Pubmed:35643766] |
| researchsquare | Dexmedetomidine Attenuates Hyperalgesia Induced By Brachial Plexus Root Avulsion By Restoring The GLT-1 Function Via PKA Signaling[] |
| Mljekarstvo | Th1/Th2 cytokine polarization in milk according to different pathogens causing subclinical mastitis in cows[] |
| Biointerface Research in Applied Chemistry | Promising Therapeutic Efficacy of Trigonella-foenum graecum and Bone Marrow-Derived Mesenchymal Stem Cells on Skeletal Muscle Atrophy in Experimental?…[] |
| Protective effects of carbon dots derived from Rhei radix et rhizoma carbonisata on DSS (dextran sulfate sodium)-induced ulcerative colitis[] | |
| Research Square | Analysis of IL-10 and IL-35 in DPP-4 inhibitor-related bullous pemphigoid[] |
| Anti-inflammatory activity of non-selective PDE inhibitor aminophylline on the lung tissue and respiratory parameters in animal model of ARDS[] | |
| Effectiveness of Carbonic Anhydrase Inhibitor Loaded Nanoparticles in the Treatment of Diabetic Retinopathy[] |